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KMID : 0370219860300010001
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Yakhak Hoeji
1986 Volume.30 No. 1 p.1 ~ p.7
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Chemical Studies on the Alkaloidal Constituents of Codonopsis lanceolata
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Jang Young-Kyoung
Kim Sang-Yol
Han Byung-Hoon
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Abstract
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The alkaloid components in the root of Codonopsis lanceolata were studied. From the ether soluble alkaloid fraction, four beta-carboline alkaloids were isolated in crystalline state by chromatographic purification process; comp. I mp 178o, isolated yield 4.5 X 10-5%, comp. II mp 166o, 6.0 X 10-5%, comp. III mp 164o, 1.8 X 10-4% and comp. IV mp 197o, 3.5 X 10-5%. They were identified by spectral analysis and by total synthesis as being a new component N9-formylharman, and already known components in other plant 1-carbomethoxy-beta-carboline, perlolyrine and norharman.
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